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Aging is wild. One day you’re doing handstands in the grass, the next you’re Googling “why does my knee sound like popcorn?” A lot of our aches and pains come down to inflammation—the bloating, brain fog, random rashes, and that lovely mid-afternoon crash. To combat it all, I created this anti-inflammatory smoothie recipe using plant-based ingredients that combat inflammation and are packed with nutrients.
Table of contents

Why You’ll Love It
- It tastes like a tropical treat. Earthy beets and baby kale get totally balanced out by sweet pineapple, mixed berries, and fresh orange—bright, tangy, and surprisingly smooth.
- It helps calm everyday inflammation. Each ingredient is chosen to support your joints, digestion, and energy—from ginger and berries to chia seeds and leafy greens.
- It’s a 5-minute reset. Perfect after a long run, a Costco marathon, or anytime your body needs a little extra love without any fuss.
- It’s nutrient-dense without being heavy. Fiber, antioxidants, and healthy fats come together in a refreshing, 16-oz blend your body will thank you for.
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Ingredients You’ll Need
Sip on this smoothie with fresh beets, citrus fruits and anti-inflammatory ginger to recover from a Saturday morning shopping trip to Costco (never a good idea), a long run with your bestie or just another day living la vida loca. Here’s what goes into your glass, how each ingredient tastes and blends, plus the nutrition perks they bring to the party:
- Baby kale: Earthy and mildly grassy leafy green vegetable, kale blends best when mixed with liquid first. It’s rich in antioxidants like vitamin C and flavonoids that help reduce inflammation.
- Beets: Sweet, earthy, and vibrant, beets add natural color and depth. They contain betalains—powerful anti-inflammatory compounds that support heart health.
- Oranges: Bright and juicy, oranges balance earthy flavors and create a silky texture. Their vitamin C helps reduce inflammation and support immune health.
- Mixed Berries: Tart and jammy, berries thicken smoothies while delivering anthocyanins, potent antioxidants linked to reduced inflammation.
- Pineapple: Sweet with a hint of tang, pineapple blends smoothly and contains bromelain, an enzyme known for its anti-inflammatory and digestive benefits. If using fresh pineapple, cut pineapple and then freeze to chill the smoothie before blending.
- Ginger Root: Warm and spicy, ginger adds bold flavor in small amounts. Its gingerols are known to help reduce inflammation and muscle soreness.
- Coconut Oil: Lightly sweet and creamy, coconut oil blends best when softened. This healthy fat contains lauric acid, which may support immune and anti-inflammatory pathways.
- Chia Seeds: This superfood naturally thicken smoothies and provide omega-3s, fiber, and protein to support inflammation balance and fullness.
Dietary Adjustments & Substitutions
Need to swap an ingredient or accommodate a food allergy? Click the button below for tailored suggestions just for you:
How to Make Anti-Inflammatory Smoothie
- Prep your produce. Wash and chop the kale and beets. Peel the orange and remove any seeds so it’s ready for the blender. Check out my recommended blenders for smoothies.
- Blend the base. Add the kale, chopped beets, peeled orange, and water to your blender. Blend on high until everything is completely smooth, scraping down the sides if needed.
- Add the fruit and flavor boosters. Toss in the frozen mixed berries, frozen pineapple, fresh ginger root, chia seeds, and coconut oil (if using).
- Blend until creamy. Blend again on high until the smoothie is thick, creamy, and no chunks remain. If it’s too thick, add a splash more water and blend again.
- Pour and enjoy. Pour into your favorite glass or jar. Garnish with extra chia seeds or a slice of orange if you’re feeling fancy, then sip right away for the biggest nutritional boost.
Time-Saving Tip
Instead of adding multiple ingredients to your blender every time, you drop an anti-inflammatory blender bomb into your smoothie to boost anti-inflammatory support.
If you make this anti-inflammatory smoothie recipe, I’d love to hear how it turned out in the comment box below. Your feedback helps me and all the readers in this community. And if you’re interested in more plant-based recipes (and exclusive content), sign up for my weekly recipe newsletter.
Anti-Inflammatory Smoothie
Ingredients
- ½ cup kale
- ½ cup beets peeled and chopped
- ¾ cup water
- ½ orange peeled
- 1 cup mixed berries frozen
- ½ cup pineapple frozen
- 1 teaspoon ginger root peeled
- 2 tablespoon chia seeds
- 1 teaspoon coconut oil optional
Instructions
- Add kale, beets, water and orange to blender container.
- Puree on high until the mixture is smooth. Scrape down the sides of chunks of the green stick to the sides of the blender.
- Add remaining ingredients and blend again on high until everything is well combined and smooth.
Helpful Tools
Notes
- Carrots can be substituted for the beets.
- Mango can be substituted for the pineapple.
- Baby kale or spinach can be used to make the smoothie less bitter.
- Use at least one frozen fruit for a refreshingly cool smoothie.
Nutrition
Did you make this recipe?
Leave a review for a chance to win signed copies of my cookbooks!Common Questions
Yes—anti-inflammatory smoothies taste amazing when you balance earthy ingredients (like kale or beets) with naturally sweet fruits (like pineapple, orange, or berries). A little ginger or citrus helps brighten everything up too.
You can have this smoothie every single day, yet feel free to start with just a few times a week to see how your body adjusts. This can be a powerful addition to your routine if you’re working on reducing inflammation.
To mask the taste of beets or leafy greens, add more ginger, pineapple, orange, or berries to help cut the “earthiness.”
Yes, you can make this anti-inflammatory smoothie in advance to save time. Blend it the night before and refrigerate in a sealed jar (drink within 24 hours). Or try freezing meal prep smoothie packs with pre-measured ingredients and dump them into the blender when ready. Another options is to make smoothie cubes (freeze the smoothie in an ice tray) and re-blend with liquid when needed.
















Made this while on a cleanse and it was one of my favorite smoothies still! I come back to it — it’s the only way I like beets!
Such a great source of potassium. Thanks for posting and thus likely encouraging others to try, Susanne.
#6 of fat burning smoothies, refreshing, very tasty! It’s a keeper.
I can’t do beets. I put a whole orange in w a tablespoon of flax/chia seeds, 1/4 tsp of turmeric powder & 1/2 tsp of cleanse powder (includes Noni fruit, Soursop leaf, Turmeric, Moringa, Bele spinach, Papaya leaf &Bacopa). Both powders from Kauai Farmacy.
Great job making it work for you. Rawking it!
Why does this recipe show 155 calories on one page and 336 calories on another page?
Thanks for letting me know— this page has the correct nutritional data for this smoothie (I just updated the other page to reflect this). I must of been multi-tasking when I worked on that blog post. 🙂
I’m wondering about the high amount of sugar in this recipe.
You list 32 g of sugar.
If Google is correct, that equals 7.66 TABLESPOONS of SUGAR !
I realize that this is fruit sugar, but it still seems to be way too much to ingest at one time.
Hi Steve! You’re correct, this is fruit sugar which is different from your average granulated sugar etc.
So excited to make this smoothie! Any recommendations for a substitution for the orange?
I don’t know if you can’t have citrus, but adding a lemon instead would be delicious. You can also just add an extar 1/2 cup frozen pineapple as well to keep it nice and sweet if you don’t have an orange.
Can pre-cooked beets from Costco be used instead of raw?
Hi Ginger! I typically use raw beets, yet you can definitely try to use the pre-cooked beets.
Check out Dr. Jorge Flechas on why people in two countries don’t have arthritis/inflamation.
Boron?
Thanks for the info, Ken.
Are these beets or carrots fresh or cooked?
Hi Pavle! No need to cook them if your blender can handle it. We use raw beets, peeled and chopped typically.
This was so easy and scrumptious. My husband even loved it. My question is how long will this last in the fridge if I make a big batch?
Hi Sandy! I wouldn’t leave a big batch in the fridge for long. It will start to separate and the frozen fruit will begin to thaw.
Perfect to start my day! My alterations were spinach as I was out, left peel on orange, I had no pineapple (bummer), carrot and beet powder used, and subbed with olive oil! Yum, Thank you!!!!
Hi Dee! Sounds like you made some great alterations to make this one work for you!
I could not live without this daily. I just never tire of it. My only modification is to add lemon juice bc I love a tart punch in the face and I feel it cuts the very veggie taste of the beets. I also have started blending it two times and it gets super liquidy and silky and smooth. I opt for baby spinach. It is just so delicious and I feel better after I have one.
Great idea to add lemon, Dawn! I’ll have to give it a try sometime.
I found this recipe after looking for an anti-inflammatory smoothie to make for being sick. I’m dealing with pleurisy in my lung and have had bronchitis. I’ve been on 2 rounds of steroids and 2 rounds of antibiotics now. I made this smoothie today, and within an hour or so my breathing is better and the pain is subsiding in my chest. My Ninja didn’t blend it well, so I ate it more than I drank it. However, I do believe that this is what may help me get my health back. Thank you sincerely for sharing this smoothie recipe. I’ve been sick for a month now, and as a really healthy person I’ve been at a loss at what to try next. So I’m putting more emphasis on nutrition. Thanks again.
I wish I could give you a buy warm hug right now— I know how frustrating and exhausting it can be when your body isn’t cooperating. I hope adding more nutrients to your body and eating more plants will help you recover. You wouldn’t be the first! If you decide to upgrade your blender, check out the Best Vitamix Deals blog post I update monthly to get the best blender out there (you won’t regret it): https://simplegreensmoothies.com/best-vitamix-sales/
Loved this. I made it as the recipe says using spinach instead of kale (with a little measuring with my heart anyway). The little kick of ginger makes this delicious. It just became one of our favorites in our breakfast rotation. Thank you!
Hi Susan! Love the swap of spinach instead of kale! I’m more of a spinach girl myself. Keep up the rawkin’ job!